Metabolomics,Metabonomics and Metabolite Profiling

Publisher: Royal Society of Chemistry
Number Of Pages: 287
Publication Date: 2007-11-19
ISBN-10 / ASIN: 0854042997
ISBN-13 / EAN: 9780854042999
Binding: Hardcover

Product Description:
The completion of gene sequencing has resulted in an intensified investigation of the proteome and metabolome Metabolite profiling methods used for disease diagnosis have been expanded with the advent of new technology and are being applied extensively in the quest for the discovery of new markers for diseases. In this comprehensive resource the Editor draws together experts from the field and provides an insightful introduction into the technology and methodology. Metabolomics, Metabonomics And Metabolite Profiling covers a broad range of topics. This is a must have, up-to-date, reference which will appeal to academics, students, technicians and professionals working in, or joining this field.

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Bioinformatics and Drug Discovery (Methods in Molecular Biology) by: Richard S. Larson (Editor)

Publisher: Humana Press
Number Of Pages: 456
Publication Date: 2005-10-01
Sales Rank: 852998
ISBN / ASIN: 1588293467
EAN: 9781588293466
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press

Book Description: 
A collection of readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the identification of specific drug candidates. The authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situations. Because these technologies are still emergent, each chapter contains an extended introduction that explains the theory and application of the technology and techniques described.

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Cancer Cytogenetics: Methods and Protocols (Methods in Molecular Biology)

Publisher: Humana Press
Number Of Pages: 296
Publication Date: 2003-03-10
ISBN-10 / ASIN: 1588290808
ISBN-13 / EAN: 9781588290809

Product Description:
The Royal Marsden NHS Trust, Surrey, UK. Text describes in detail the key cytogenetic and FISH techniques used in the genetic analysis of human malignancies and how to interpret the results. Each protocol contains novel ideas and time-saving techniques.

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Chromosome Analysis Protocols (Methods in Molecular Biology, 29)

Chromosome Analysis Protocols (Methods in Molecular Biology, 29) by: John R. Gosden
Publisher: Humana Press
Number Of Pages: 508
Publication Date: 1994-02-07
Sales Rank: 3411347
ISBN / ASIN: 0896032892
EAN: 9780896032897
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press

Book Description:
Clear, step-by-step instructions provide you with all the techniques used in both classical and molecular cytogenetics. The emphasis is on the use of human material, but the techniques are designed to be readily applicable to other animal chromosomes. Chapters feature methods used in the preparation of chromosomes, in analyzing chromosomes directly at the light-microscope level, and in molecular genetics techniques.

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Genetics of Movement Disorders By Stefan M. Pulst

Genetics of Movement DisordersBy Stefan M. Pulst
Publisher: Academic Press
Number Of Pages: 561
Publication Date: 2002-10-03
ISBN-10 / ASIN: 0125666527
ISBN-13 / EAN: 9780125666527
Binding: Hardcover

Product Description: 
Hereditary or genetic diseases featuring involuntary movements constitute a major aspect of the practice of neurology, functional neurosurgery, genetics, and many areas of basic and applied neuroscience research. Describing the current knowledge on these disorders, Genetics of Movement Disorders brings together information essential for clinicians, geneticists, and neuroscientists in one source. Utilizing a convenient and accessible format, the book is designed to allow easy identification of relevant information, with the overall organization of topics following established phenotypic classifications of movement disorders such as Parkinsonian syndromes, chorea, ataxia, and major categories of diseases grouped by gene locus. This book broadly appeals to neurologists, neuroscientists, geneticists, as well as cell and molecular biologists and hematologists.Key Features* Consistently formatted to present a clinical description of the disorder, followed by an in-depth analysis of the mutation and function of the mutated gene including cellular and animal models*

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Process Chemistry in the Pharmaceutical Industry

Process Chemistry in the Pharmaceutical Industry
Publisher: CRC ISBN: 0824719816 edition 1999 PDF 500 pages 14,7 mb

Bristol-Myers Squibb Co., New Brunswick, NJ. Reference highlights new strategies for aggressive drug development programs. Includes 12 case studies on agents such as inhibitors and antagonists, 'green chemistry', and new medicinal compounds. For chemists and those entering pharmaceutical discover and development fields. Illustrated.

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Chemistry and Pharmacology of Anticancer Drugs by: David E. Thurston

Chemistry and Pharmacology of Anticancer Drugs by: David E. Thurston
Publisher: CRC Press | 1 Dec 2006 | ISBN: 0849392195 | Pages: 312 | PDF | 6.6 MB

Following a review of cancer causes and progression, current treatments, and the philosophy of drug discovery, this comprehensive work surveys anticancer agents currently in use or in advanced stages of clinical trials, including biological agents. Ideal for those involved in anticancer drug research, the book provides molecular structures for each agent and discusses their history, chemistry, mechanisms of action, structure-function relationships, relevant pharmacology, cytotoxicity, side effects, and formulation issues. It also discusses new research tools, methodologies, tumor-targeting strategies, and the emerging areas of oncogenomics and chemoprevention.

While drug therapies developed in the last 50 years have markedly improved the management of some types of cancers, treatment outcomes, and drug side-effects for the most common types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells. Chemistry and Pharmacology of Anticancer Drugs is a comprehensive survey of all families of anticancer agents currently in use or in advanced stages of clinical trials, including biologicals.

The book is unique in providing molecular structures for all anticancer drugs, discussing them in terms of history, chemistry, mechanism of action, structure-function relationships, and pharmacology. It also provides some relevant information on side effects, dosing, and formulation. The author, a renowned scientist in cancer research and drug development, also provides up-to-date information on the drug discovery process, including new research tools, tumor-targeting strategies, and fundamental concepts in the emerging areas of personalized medicine (e.g., oncogenomics) and chemoprevention.

Chemistry and Pharmacology of Anticancer Drugs is an indispensable resource for cancer researchers, medicinal chemists, and other biomedical scientists involved in the development of new anticancer treatments. Its breadth of coverage also makes it suitable for undergraduate and postgraduate courses in medicine, pharmacy, nursing, and related disciplines.

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Pharmaceutical Drug Analysis

Ashutosh Kar "Pharmaceutical Drug Analysis"
New Age Publications English 2005-12-01 ISBN: 8122415822 564 pages PDF 3,2 MB

During the past two decades, there have been magnificent and significant advances in both analytical instrumentation and computerized data handling devices across the globe. In this specific context the remarkable proliferation of windows-based computer software stretched overwhelmingly towards instrument control, real time data handling abilities and the ultimate usage of Laboratory Information Management Systems (LIMS) are surprisingly noteworthy.

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Pharmaceutical Microbiology

Pharmaceutical Microbiology
Publisher: New Age International | Pages:384 | Aug, 2007 | ISBN:8122422009 | PDF | 3 MB

The textbook on `Pharmaceutical Microbiology` has been adequately developed and expanded according to the AICTE- Approved Syllabus-2000 meant for the Pharmacy Degree Programme across all the Indian Universities, and others abroad offering similar curricula.

Specific attention has been duly paid to the presentation of each chapter that essentially includes: brief introduction, theoretical aspects, classification, neat and vivid diagrammatic illustrations of figures-graphics-equipments, lucid explanations, supportive classical examples, and profusely supplemented with explanatory`foot notes`-references in addition to further reading bibliography.

The text content runs over ten chapters that may prove to be of paramount interest and enormous readability not only confined to the B.Pharm., students but also to various M.Sc., academic curricula in such disciplines as: Food Microbiology, Environmental Science, Microbiology etc.

Key Features IncludeConcise and exhaustive presentation of scientific informations from several sources.A wealth of theoretical information that opens newer possibilities.Detailed classification of various microbial aspects.Pharmaceutical assays and methodologies.Comprehensive index includes significant terminologies.Well documented statement of facts.

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