Insertional Mutagenesis Strategies in Cancer Genetics
By Adam J. Dupuy, David A. Largaespada
* Publisher: Springer
* Number Of Pages: 150
* Publication Date: 2010-12-01
* ISBN-10 / ASIN: 1441976558
* ISBN-13 / EAN: 9781441976550
Product Description:
The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.
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