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An Introduction to Clinical Pharmaceutics
Pharmaceutical Press | 2010-03-09 | ISBN: 0853696918 | 17 pages | PDF | 50 MB
This is an introductory undergraduate textbook that considers the importance of pharmaceutics and pharmaceutical dosage form design by considering the clinical use of modern drugs. Although a knowledge of pharmaceutics (physical chemistry applied to pharmaceuticals) is essential in the design and manufacture of modern pharmaceutical dosage forms, a knowledge of the interaction of dosage forms with the body (clinical pharmaceutics) is essential in the practising pharmacist. This textbook will thus describe a variety of dosage forms and their clinical importance and use. The use and behaviour of dosage forms in different age groups and patient groups will also be considered along with recent developments such as personalised therapies and genomics. All of the principles underpinning clinical pharmaceutics will be described using relevant examples from the recent literature and clinical case studies.Download
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Alexander T. Florence, Juergen Siepmann, "Modern Pharmaceutics, Fifth Edition, Volume 1: Basic Principles and Systems"
Informa Healthcare | 2009 | ISBN: 1420065645 | 656 pages | PDF | 11,5 MB
With over 100 illustrations, Volume 1 addresses the core disciplines of pharmaceutics (absorption, PK, excipients, tablet dosage forms, and packaging), and explores the challenges and paradigms of pharmaceutics.
Features:
NEW CHALLENGES AND PARADIGMS IN PHARMACEUTICS - Explores fundamental research in physical phenomena related to dose-form design at a time when much research is biological in nature
COVERS NEW TECHNIQUES FOR IN VIVO IMAGING DOSE FORMS - Apart from Gamma scintigraphy, until recently there have been few means of following real time behavior of formulations in vivo
DETAILED EXPLANATION OF CHEMICAL KINETICS AND DRUG STABILITY - Includes many drug structural diagrams to illustrate points covered in the text
HOW BEST TO CARRY OUT PREFORMULATION - Discusses procedures for examining drugs and their physical chemistry prior to designing the appropriate formulations
THE LATEST IN POWDER TECHNOLOGY - Explains the intelligent use of powders in pharmaceutics
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Biopharmaceuticals in Plants: Toward the Next Century of Medicine By Kathleen Laura Hefferon
CRC Press | Pages: 224 | 2009-11-10 | ISBN 1439804745 | PDF | 3 MB
Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been made with respect to the development of vaccines, antibodies, and other therapeutic proteins. Biopharmaceuticals in Plants: Toward the Next Century of Medicine provides a comprehensive survey of all major aspects of the development and production of plant-made biopharmaceuticals.
Accompanied by an exhaustive list of references to facilitate further study, this critical volume:
Describes the theory and practice of modern plant transformation techniques with respect to nuclear and plastic genomes Outlines the steps involved in the generation of transgenic plants Discusses the engineering of plant virus expression vectors for transient expression of vaccine proteins and other therapeutics in plant tissue Addresses the significant role of glycosylation in the production of plant-made mammalian proteins Investigates the basis of mucosal immunity using plant-based oral vaccines Examines the scale-up of plant-derived vaccine and therapeutic proteins in entire crops or in large batch cell suspension cultures Explores the development of clinical trials utilizing plant-derived biopharmaceutical proteins Evaluates risks and biosafety concerns regarding plant-derived pharmaceuticals
The book concludes with a discussion of the future of plant-based vaccines and other therapeutic proteins with respect to commercial viability and as a tool to improve global public health. Far-reaching in its scope, this text is a baseline reference that students and researchers in a broad range of fields such as medicine, plant science, biotechnology, crop science, natural products chemistry, and engineering will consult regularly. It will also serve as a useful tool for individuals and companies seeking to invest in this dynamic area.
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Written by a panel of experts, this book covers every stage of drug development, from candidate drug selection to commercial formulation. It provides practical reference and pragmatic guide on what studies need to be undertaken, for what reasons, and at what key stages of the drug development process. Going beyond coverage of preformulation, the book discusses biopharmaceuticals, drug delivery, formulation, and process development aspects of product development. The contributing authors share their experience and expertise in significant chapters divided into three useful sections: Aiding Candidate Drug Selection, Early Drug Development, and From Product Design to Commercial Dosage Form. Features.
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Free eBook Download PDF Handbook of Pharmaceutical Excipients, 6th Edition
Publisher: Pharmaceutical Press | Pages: 917 | 2009-07-31 | ISBN 0853697922 | PDF | 17 MB
The Handbook of Pharmaceutical Excipients" is internationally recognised as the authoritative source of information on pharmaceutical excipients. PDF Handbook of Pharmaceutical Excipients eBook Free Download. "The Handbook of Pharmaceutical Excipients" is a comprehensive guide to the uses, properties and safety of pharmaceutical excipients and is an essential reference for those involved in the development, production, control or regulation of pharmaceutical preparations.
The handbook collects together essential data on the physical properties of excipients as well as providing information on their safe use and potential toxicity. All monographs are also thoroughly cross-referenced and indexed to allow their identification by chemical, non-proprietary or trade names.
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Pharmaceutical Manufacturing Encyclopedia (2 Volume Set) by Marshall Sittig (Repost)
Publisher: William Andrew; 2 edition (January 15, 1988) | ISBN: 0815511442 | Pages: 1780 | PDF | 23.28 MB
This second edition of the best seller, more than double the size of the previous edition describes manufacturing processes for approximately 1300 pharmaceuticals currently marketed as trade-name products around the world. Pertinent process information has been obtained from the patent literature, and references for other synthetic methods and pharmacology are cited. A 2000-entry Raw Materials Index will quickly tell you in which drugs the raw materials are utilized. A 12,000-entry Trade Name Index completes the book. It has been estimated that, in 1990, 40% of the drug market will be generic. With total sales volume over $100 billion, the pharmaceutical industry provides greater profit margins than other sectors of the chemical industry.
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Affinity Capillary Electrophoresis in Pharmaceutics and BiopharmaceuticsInforma Healthcare; 1 edition | January 14, 2003 | ISBN-10: 0824709519 | 384 pages | PDF | 2.3 Mb
Martin-Luther-University, Halle-Wittenberg, Germany. Text presents recent breakthroughs and techniques in affinity capillary electrophoresis to measure and determine the physicochemical and thermodynamic parameters of drug compounds. Offers strategies to explore and characterize interactions between drugs.
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Alexander T. Florence, Juergen Siepmann, "Modern Pharmaceutics, Fifth Edition, Volume 1: Basic Principles and Systems"
Informa Healthcare | 2009 | ISBN: 1420065645 | 656 pages | PDF | 11,5 MB
With over 100 illustrations, Volume 1 addresses the core disciplines of pharmaceutics (absorption, PK, excipients, tablet dosage forms, and packaging), and explores the challenges and paradigms of pharmaceutics.
Features:
NEW CHALLENGES AND PARADIGMS IN PHARMACEUTICS - Explores fundamental research in physical phenomena related to dose-form design at a time when much research is biological in nature
COVERS NEW TECHNIQUES FOR IN VIVO IMAGING DOSE FORMS - Apart from Gamma scintigraphy, until recently there have been few means of following real time behavior of formulations in vivo
DETAILED EXPLANATION OF CHEMICAL KINETICS AND DRUG STABILITY - Includes many drug structural diagrams to illustrate points covered in the text
HOW BEST TO CARRY OUT PREFORMULATION - Discusses procedures for examining drugs and their physical chemistry prior to designing the appropriate formulations
THE LATEST IN POWDER TECHNOLOGY - Explains the intelligent use of powders in pharmaceutics
Download
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FASTtrack: Pharmaceutics - Drug Delivery and Targeting
Publisher: Pharmaceutical Press | Pages: 160 | 2009-10 | ISBN 0853697620 | PDF | 5 MB
This is a revision guide for students providing bullet points of basic information on pharmaceutics - delivery and targeting."FASTtrack" is a new series of indispensable revision guides created especially for undergraduate pharmacy students.The content of each title focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and an all-important self-assessment section which includes MCQs, case studies, sample essay questions and worked examples.This specific title is a basic revision guide in Pharmaceutics and the delivery and targeting of drugs. It will complement "FASTtrack: Pharmaceutics - Dosage Form and Design" by David Jones.The "FASTtrack" series provides the ultimate lecture notes and is a must-have for all pharmacy undergraduate students wanting to revise and test themselves for forthcoming exams.A "FASTtrack" website includes MCQs, sample online content and much more.
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