Thomas' Hematopoietic Cell Transplantation

Frederick R. Appelbaum, Stephen J Forman, Robert S. Negrin, Karl G. Blume, "Thomas' Hematopoietic Cell Transplantation"
Wiley-Blackwell; 4th edition (May 4, 2009) | English | 1405153482 | 1752 pages | PDF | 31.91 MB

Haematopoietic cell transplantation is the intravenous infusion of haematopoietic progenitor cells designed to establish marrow and immune function in patients with a variety of acquired and inherited malignant and non-malignant disorders. These include hematological malignancies (leukaemia, lymphoma and myeloma), non-malignant acquired bone marrow disorders (aplastic anaemia), and genetic diseases associated with abnormal haematopoiesis and function (thalassaemia, sickle cell anaemia, and severe combined immunodeficiency). Haematopoietic cell transplantation is also key in the support of patients undergoing high-dose chemotherapy for the treatment of malignant diseases for which hematological toxicity would otherwise limit drug administration (e.g. breast, germ-cell and ovarian cancers).

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